UMAP image of three cases of primary and metastatic tumors. (A) Primary lesion, inflammatory phenotype without MYB-NFIB fusion. (B) Primary lesion, immune-exclusive phenotype with MYB-NFIBSalivary ade....
2023-06-30
Schematic overview of ultrasound-triggered gas therapy. Under ultrasound irradiation, the gas released molecules are released gases, for example, NO, O2, CO, CO2, for tumor therapy.In recent years, ul....
2023-05-31
Fatty acid (FA) metabolism in cancer cells. FAs can be de novo synthesized from citrate via ATP citrate lyase (ACLY), acetyl-CoA carboxylase (ACC), and FA synthase (FASN). Exogenous FAs can enter cell....
2023-04-30
The two major angiogenic signaling pathways involved in vessel formation. Schematic representation of sequential events that take place under activation of angiogenesis. The paradigm follows the activ....
2023-03-31
Schematic illustrating the potential pathway associated with the apoptosis-inducing effect of Kuwanon-A (KA) and 5-fluorouracil (5-FU) on gastric cancer (GC) cells.Despite the application of conventio....
2023-02-28
Oncolytic virus (OV) activation of both systemic and local antitumor immunity. After OV infection, cell death, and the release of tumor-associated antigens, tumor-specific immune responses increase an....
2023-01-31
A high integrin αVβ3 level is associated with non-small-cell lung cancer metastasis and a poor prognosisMetastasis is the most prevalent cause of cancer deaths, and immunological components of the tum....
2022-12-23
MedComm
Schematic illustration of novel approaches for biomimetic precision antitumor strategies based on biological membrane-coated inorganic nanoparticlesInorganic nanoparticles have extensively revolutioni....
2022-12-08
MedComm
ENKUR inhibits MYH9 expression by recruiting the E3 ubiquitin ligase FBXW7 to promote its protein ubiquitinated degradation. Downregulated MYH9 further increased the degradation of β-catenin protein b....
2022-11-25
MedComm