MedComm-Future Medicine | Role of next-generation sequencing in revolutionizing healthcare for cancer management

Timeline of the evolution of next generation sequencing (created by BioRender).Next-generation sequencing (NGS) has emerged as a transformative technology in oncology, revolutionizing cancer diagnosti....

2024-11-30

MedComm-Biomaterials and Applications | Application of biomaterials in cardiac tissue engineering: Current status and prospects

The basic mechanism of myocardial infarction repair.Cardiovascular diseases have become one of the leading causes of death and illness worldwide, posing significant challenges to global health. Due to....

2024-11-30

MedComm-Oncology | Epigenetic remodeling under oxidative stress: Mechanisms driving tumor metastasis

Reactive oxygen species (ROS) participate in the whole process of tumor metastasis. During metastasis, ROS are always at abnormal levels due to the dynamic imbalance of the redox system of tumor cells....

2024-11-30

MedComm-Future Medicine | Enhanced prediction of preoperative mesenteric lymph node metastasis in colorectal cancer using machine learning with CT-based data

Flowchart illustrating the process of patients’ enrollment.The detection of lymph node (LN) involvement is fundamental for staging colorectal cancer (CRC) and aids in clinical decision-making. Traditi....

2024-10-31

MedComm-Biomaterials and Applications | Metal-organic frameworks-based nanomedicines to promote cancer immunotherapy: Recent advances and future directions

Applications of metal-organic framework in immunotherapy. IDO1, Indoleamine 2,3-dioxygenase-1; MOFs, metal-organic frameworks; OVA, ovalbumin; TLR, toll-like receptor; TME, tumor microenvironment.Canc....

2024-10-31

MedComm-Oncology | miRNA interplay: Mechanisms and therapeutic interventions in cancer

New technologies for studying miRNA Interactions. (A) High-throughput sequencing technologies such as RNA-seq accurately detect miRNA sequences through steps including extraction, reverse-transcriptio....

2024-10-31

MedComm-Future Medicine | Deep learning methods for protein structure prediction

Overview of traditional and modern deep learning methods for protein structure prediction.Protein structure prediction (PSP) has been a prominent topic in bioinformatics and computational biology, aim....

2024-09-30

MedComm-Biomaterials and Applications | Research progress of hydrogels in the prevention of pelvic inflammatory disease

The main causative pathogens in vaginal infections and urinary tract infections (UTIs) and their potential relationship with the intrinsic properties of hydrogels.Pelvic inflammatory disease (PID) is ....

2024-09-30

MedComm-Oncology | Extensive infiltration of CD8+ T cells and M1 macrophages is beneficial for multiple cancer patients undergoing chemotherapy

Data screening and analysis process. BLCA, bladder urothelial carcinoma; BRCA, breast invasive carcinoma; COAD, colon adenocarcinoma; HR, hazard ratio; LUAD, lung adenocarcinoma; LUSC, lung squamous c....

2024-09-30