Schematic illustrating the potential pathway associated with the apoptosis-inducing effect of Kuwanon-A (KA) and 5-fluorouracil (5-FU) on gastric cancer (GC) cells.Despite the application of conventio....
2023-02-28
Oncolytic virus (OV) activation of both systemic and local antitumor immunity. After OV infection, cell death, and the release of tumor-associated antigens, tumor-specific immune responses increase an....
2023-01-31
A high integrin αVβ3 level is associated with non-small-cell lung cancer metastasis and a poor prognosisMetastasis is the most prevalent cause of cancer deaths, and immunological components of the tum....
2022-12-23
MedComm
Schematic illustration of novel approaches for biomimetic precision antitumor strategies based on biological membrane-coated inorganic nanoparticlesInorganic nanoparticles have extensively revolutioni....
2022-12-08
MedComm
ENKUR inhibits MYH9 expression by recruiting the E3 ubiquitin ligase FBXW7 to promote its protein ubiquitinated degradation. Downregulated MYH9 further increased the degradation of β-catenin protein b....
2022-11-25
MedComm
Schematic diagram of protein phosphorylation signaling pathway of protein kinase A, G, and C (AGC)-receptor guanylate cyclase (RGC) groupProtein phosphorylation is an important post-transcriptional mo....
2022-11-03
MedComm
The altered brain and platelet key proteins and their network linkage in AD patients.Platelets may serve as a perfect peripheral source for exploring diagnostic biomarkers for Alzheimer's disease (AD)....
2022-10-13
MedComm
Mechanisms of secondary resistance of small molecule inhibitors and countermeasuresCompared with traditional therapies, targeted therapy has merits in selectivity, efficacy, and tolerability. Small mo....
2022-10-13
MedComm
Crosstalk in the metabolism organs of cancer cachexia. Cancer cachexia is a complex systemic catabolism syndrome characterized by muscle wasting. It affects multiple distant organs and their crosstalk....
2022-09-10
MedComm