Schematic illustration of various lipid-based nanocarriers with phospholipid, ethanol, and surfactant (liposome, transethosome, transferosome, and ethosome).The growing need for innovative drug delive....
2023-10-31
Number of publications found in the SciFinder® search for covalent inhibitors closely related to targeting different amino acid residues.Covalent inhibitors have been a rapidly growing field in drug d....
2023-10-31
Metabolic profile of normal and tumor cells. Normal cells provide energy primarily through the tricarboxylic acid cycle, while tumor cells provide energy primarily through glycolysis even in the prese....
2023-09-30
Prokaryotes to eukaryotes: MLT-preserved characteristics.Cancer is one of the most prevailing causes of mortality worldwide. Standard therapies for cancer patients include surgical intervention, chemo....
2023-09-30
The structures of approved macrocyclic drugs and investigating macrocyclic compounds for cancer therapy.(A) Macrocyclic compounds to target cancer development. Compounds 1–2: macrocyclic peptide drugs....
2023-09-30
Comparison between traditional chemotherapy and chemoimmunotherapy. Traditional standard chemotherapy contained alkylating agents, platinum, antimetabolites, microtubule inhibitors, and so on. Each of....
2023-08-31
Classification of the thermosensitive hydrogel.The scientific community has widely recognized thermosensitive hydrogels as highly biocompatible material with immense potential in drug delivery systems....
2023-08-31
The activation and translocation of STING. STING interacts with STIM1 and localizes on the ER. When STING is not yet activated, it is in a dimeric state with an open conformation. When STING is activa....
2023-08-31
Large-scale AI models. (A) Comparison of large-scale AIs with deep learning and machine learning. (B) Overview of the most recent advanced large-scale AI models and their sizes. A summary of the lates....
2023-07-31