Mechanisms of CRISPR/Cas system, BE and PEThe discovery and development of the CRISPR/Cas system is a milestone in precise medicine. CRISPR/Cas nucleases, base-editing (BE) and prime-editing (PE) are ....
2022-10-14
Mol Biomed
The gut microbiota helps maintaining the balance of the mucosal barrier and immune homeostasisThe gut microbiota is critical to human health, such as digesting nutrients, forming the intestinal epithe....
2022-10-11
Mol Biomed
The coat protein mediated vesicle formationIntracellular vesicle trafficking is the fundamental process to maintain the homeostasis of membrane-enclosed organelles in eukaryotic cells. These organelle....
2022-09-21
Mol Biomed
C11ORF94 is a vertebrate derived transmembrane protein highly expressed in testisSperm-oocyte membrane fusion is necessary for mammalian fertilization. The factors that determine the fusion of sperm w....
2022-09-02
Mol Biomed
Cellular properties of the photosensitizer ICG in vitroPhotodynamic therapy (PDT) has shown impressive therapeutic effects on various types of cancers by reactive oxygen species (ROS) generation and i....
2022-08-17
Mol Biomed
Expression of miR-379-5p is decreased in vitro/in vivo/in clinic.Lipotoxicity induced by the overload of lipid in the liver, especially excess free cholesterol (FC), has been recognized as one of driv....
2022-08-10
Mol Biomed
Classification of infective human viral diseases and their characteristic sub division and familyA virus enters a living organism and recruits host metabolism to reproduce its own genome and proteins.....
2022-07-15
Mol Biomed
Schematic diagram of obtain CDR3 of neutralizing antibodies against SARS-CoV-2Although the SARS-CoV-2 vaccine has been widely used worldwide, not all individuals can produce neutralization antibodies,....
2022-07-05
Mol Biomed
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) dysregulates antiviral signaling, immune response, and cell metabolism in human body. Viral genome and proteins hijack host metabolic netwo....
2022-08-09