Antitumor effects of oncolytic virus (OVs) in brain tumor. (1) OVs can selectively infect tumor cells and induce tumor cells lysis including apoptosis, pyroptosis, and necroptosis. (2) Innate immune r....
2023-10-31
Schematic illustration of various lipid-based nanocarriers with phospholipid, ethanol, and surfactant (liposome, transethosome, transferosome, and ethosome).The growing need for innovative drug delive....
2023-10-31
Number of publications found in the SciFinder® search for covalent inhibitors closely related to targeting different amino acid residues.Covalent inhibitors have been a rapidly growing field in drug d....
2023-10-31
Metabolic profile of normal and tumor cells. Normal cells provide energy primarily through the tricarboxylic acid cycle, while tumor cells provide energy primarily through glycolysis even in the prese....
2023-09-30
Prokaryotes to eukaryotes: MLT-preserved characteristics.Cancer is one of the most prevailing causes of mortality worldwide. Standard therapies for cancer patients include surgical intervention, chemo....
2023-09-30
The structures of approved macrocyclic drugs and investigating macrocyclic compounds for cancer therapy.(A) Macrocyclic compounds to target cancer development. Compounds 1–2: macrocyclic peptide drugs....
2023-09-30
Comparison between traditional chemotherapy and chemoimmunotherapy. Traditional standard chemotherapy contained alkylating agents, platinum, antimetabolites, microtubule inhibitors, and so on. Each of....
2023-08-31
Classification of the thermosensitive hydrogel.The scientific community has widely recognized thermosensitive hydrogels as highly biocompatible material with immense potential in drug delivery systems....
2023-08-31
The activation and translocation of STING. STING interacts with STIM1 and localizes on the ER. When STING is not yet activated, it is in a dimeric state with an open conformation. When STING is activa....
2023-08-31