MedComm-Future Medicine | Unraveling the influence of metabolic signatures on immune dynamics for predicting immunotherapy response and survival in cancer

Overall Survival analysis in metabolism-based classes. (A) Nonnegative matrix factorization clustering algorithm by metabolism genes in training cohort. (B) Kaplan–Meier curve of patients in the train....

2024-06-30

MedComm-Biomaterials and Applications | Evaluation of cell-laden three-dimensional bioprinted polymer composite scaffolds based on synthesized photocrosslinkable poly(ethylene glycol) dimethacrylate with different molecular weights

Schematic representation of bioprinting using poly(ethylene glycol) dimethacrylate (PEGDMA). LAP, lithium phenyl-2,4,6-trimethyl benzoyl phosphinate.This manuscript aims to three-dimensional bioprint ....

2024-06-30

MedComm-Oncology | Clinical homologous recombination repair gene reversion analysis identifies mechanisms of resistance to PARP inhibitors and platinum-chemotherapy

Study design. The 25 pre-defined HRR genes covered by the NGS panel is shown. Patient screening flow is demonstrated with the rationale of the four-tier classification. HRR, homologous recombination r....

2024-06-30

MedComm-Future Medicine | Current progress in chimeric antigen receptor T-cell therapy for malignant tumors

The chimeric antigen receptor (CAR) structure of four generations. The development process and structural changes of CAR-T cells from the first generation to the fourth generation. The arrow points to....

2024-05-31

MedComm-Biomaterials and Applications | Customized 3D-printed heterogeneous porous titanium scaffolds for bone tissue engineering

3D printing of physical objects and structural parameters. (A) Physical images of uniform gradient scaffolds and dual gradient scaffolds prepared by selective laser melting (SLM). (B, C) Definition of....

2024-05-31

MedComm-Oncology | Pathogenic mechanisms and etiologic aspects of Mycobacterium avium subspecies paratuberculosis as an infectious cause of cutaneous melanoma

Mycobacterium avium subspecies paratuberculosis (MAP) exposure and related risk factors for cutaneous melanoma. Cutaneous melanoma is hypothesized to result from the interplay of MAP exposure, genetic....

2024-05-31

MedComm-Future Medicine | A biodegradable cardiac electrotherapy device paving the way for autonomous transient implants

Bioresorbable pacemaker for cardiac rhythm control. (A) An illustration showing a wireless system for monitoring and pacing heart rhythm and nonhospitalized termination. (B) An illustration showing th....

2024-04-30

MedComm-Biomaterials and Applications | Carbon nanomaterials-based electrically conductive scaffolds for tissue engineering applications

(A) Carbon nanomaterials and their use in various tissue engineering applications. Produced using www.biorender.com. (B) number of publications on carbon-based tissue engineering scaffolds for differe....

2024-04-30

MedComm-Oncology | Transpiration of neurological phenomena in cancer: Long-term depression (LTD) abrogates cancer stem cell memory and sensitizes it to metabolic therapy

Visualization of neuronal-like cells in HCT-116, MDA-MB-231, 4T1, and B16-F10 cell lines using transient transfection of pPalmitoyl-mTurquiose2 plasmid (scale bar: 20 µm).Therapy resistance and recurr....

2024-04-30