MedComm-Future Medicine | VDDB: A comprehensive resource and machine learning tool for antiviral drug discovery

Potential antivirals in VDDB. (A) Annotated entry for each vaccine. (B) Annotated entry for each antibody. (C) Annotated entry for each small molecule. (D) Classification of viruses.Virus infection is....

2023-01-31

MedComm-Biomaterials and Applications | DNA origami technology for biomedical applications: Challenges and opportunities

DNA origami technology. (A) Schematic shows the fabrication process of classic DNA origami nanostructures. (B) Representative two-dimensional DNA origami shapes. (C) Representative three-dimensional m....

2023-07-31

MedComm-Biomaterials and Applications | Nanotechnology connecting copper metabolism and tumor therapy

The strategy and applications of copper metabolism-based cancer therapy.Copper (Cu) is an essential trace element in the human body that is involved in the formation of several natural enzymes, such a....

2023-06-30

MedComm-Biomaterials and Applications | Recent progress in orodispersible films-mediated therapeutic applications: A review

(A) Orodispersible films (ODFs) embedded with poorly water-soluble active pharmaceutical ingredients (APIs) formulated by various formulation strategies (image reprinted with permission from Ref.Orodi....

2023-05-31

MedComm-Biomaterials and Applications | Nanobiotechnology-mediated radioimmunotherapy treatment for triple-negative breast cancer

Mechanism of radiotherapy-induced abscopal effect combined with immunotherapy. CTLA-4, cytotoxic T-lymphocyte-associated antigen 4; PD-1, programmed death 1; PD-L1, programmed death-ligand 1; TNBC, tr....

2023-04-30

MedComm-Biomaterials and Applications | Dendrimer and dendrimer gel-derived drug delivery systems: Breaking bottlenecks of topical administration of glaucoma medications

Two major barriers to topical ocular drug delivery. Reprinted with permission from Li et al.Due to high structural flexibility, multidrug carrying capability, and tunable size, dendrimers have been us....

2023-03-31

MedComm-Biomaterials and Applications | 2-Hydroxy-1,4-naphthoquinone [Lawsone] integrated rare-earth hybrid materials as biocompatible UV/IR filter agents

Crystal phase and chemical interphase characterization of rare-earth systems and their hybrids: (A, B) XRD patterns of as-dried rare-earths and rare-earth hybrid systems, respectively; (C) FTIR spectr....

2023-02-28

MedComm-Biomaterials and Applications | Applications of scanning ion conductance microscope in biomedical fields

Imaging modes of scanning ion conductance microscopy (SICM). (A) In direct current (DC) mode, once the probe is close to the sample, the ion electricity decays rapidly. This key feature provides a fee....

2023-01-31

MedComm-oncology | Delivering CAR-T cells into solid tumors via hydrogels

Schematic illustration of the regional codelivery of CAR-T cells and therapeutic agents via hydrogels for the treatment of solid tumors. CAR, chimeric antigen receptor.Chimeric antigen receptor (CAR)-....

2023-07-31