MedComm-Future Medicine | Long-Term Clinical Outcomes of Treatments for In-Stent Chronic Total Occlusions: A Real-World Study Based on Different Strategies of Revascularization

Study flow chart. CABG, coronary artery bypass graft surgery; DCB, drug-coated balloon; DES, drug-eluting stents; IS-CTO, in-stent chronic total occlusion; PCI, percutaneous coronary intervention; POB....

2025-02-28

MedComm-Biomaterials and Applications | One-pot synthesis of tunable fluorescent polyethylene glycol (PEG) polymer for antimicrobial and anticancer theranostics

An overview of the synthesis procedure of fluorescent PEG benzimidazolium-tagged acridine carboxylic acid mixture (PEG-b-ACA) and its applications. PEG, poly (ethylene glycol).Poly (ethylene glycol) (....

2025-02-28

MedComm-Oncology | Tumor Metastasis: Mechanistic Insights and Therapeutic Intervention

Phases of metastasis. Through the process of epithelial–mesenchymal transition (EMT) and interaction with stromal cells, primary tumor cells become more invasive and invade the vasculature or lymphati....

2025-02-28

MedComm-Future Medicine | Machine-learning-based integration of tumor microenvironment features predicting immunotherapy response

Study overall design. (A) The evaluation of tumor microenvironment (TME) based on the 83 immunotherapy responsiveness-related features. (B) The construction of immunotherapy resistance score (IRS) bas....

2025-01-31

MedComm-Biomaterials and Applications | Biofilm formation in cardiovascular infection and bioengineering approaches for treatment and prevention

Biofilm-related infections and pathogens of the cardiovascular system.At present, cardiovascular infection such as infective endocarditis (IE) has become a major disease with a high mortality rate. Th....

2025-01-31

MedComm-Oncology | Unraveling the underlying mechanisms of cancer stem cells in therapeutic resistance for optimizing treatment strategies

Signaling pathways related to cancer stem cells (CSCs) and mutations within stem cells (SCs). In the Wnt signaling pathway, Disheveled (DVL) is activated, leading to the inhibition of GSK3β, which occ....

2025-01-31

MedComm-Future Medicine | The recent development, application, and future prospects of muscle atrophy animal models

Various models for studying muscle atrophy. Muscle atrophy is a primary characteristic of both sarcopenia and cachexia, significantly impacting physical function and quality of life. This figure illus....

2024-12-31

MedComm-Biomaterials and Applications | Biomimetic nanosystems based on cell membranes (BNCMs) for cancer immunotherapy

Schematic illustrations of biomimetic nanosystems based on cell membranes for cancer immunotherapy. (A) Graphical illustration of the cell types for biomimetic nanosystems based on cell membranes for ....

2024-12-31

MedComm-Oncology | Oxidative stress and cellular senescence: Roles in tumor progression and therapeutic opportunities

Oxidative stress theory of aging. An imbalance between the antioxidant system and oxidants inevitably leads to oxidative stress, resulting in damage to cellular structures and macromolecules such as p....

2024-12-31