MedComm-Future Medicine | Computed tomography-based artificial intelligence in lung disease—Chronic obstructive pulmonary disease

The workflow of computed tomography (CT)-based artificial intelligence applied in chronic obstructive pulmonary disease (COPD) management. Features of emphysema and bronchial tree will be extracted by....

2024-02-29

MedComm-Biomaterials and Applications | Management of peripheral nerve injuries using natural based biomaterials and their derivatives: Advances and prospective

The schematic diagram shown above depicts the drug distribution composite scaffold with a sandwich-like structure. (Figure is drawn from Bio render software).The management of peripheral nerve injurie....

2024-02-29

MedComm-Oncology | The hidden architects of glioblastoma multiforme: Glioma stem cells

Cell of origin of glioblastoma multiforme (GBM). There has always been a controversy in regard to the origination of GBM. While the precise cell of origin remains elusive, evidence suggests that neura....

2024-02-29

MedComm-Future Medicine | AlphaMissense, a groundbreaking advancement in artificial intelligence for predicting the effects of missense variants

Basic framework of AlphaMissense model. AlphaMissense utilizes a missense variant as input to predict its likelihood of being pathogenic. The algorithm is refined using population frequency data of va....

2024-01-31

MedComm-Biomaterials and Applications | Nanotechnology-based CRISPR/Cas9 delivery system for genome editing in cancer treatment

Schematic of the CRISPR/Cas9 system and its nanotechnology delivery methods. The CRISPR/Cas9 system can be delivered in the forms of DNA, mRNA/sgRNA, or ribonucleoprotein (RNP). The gene editing tools....

2024-01-31

MedComm-Oncology | Epigenetic regulation in cancer therapy: From mechanisms to clinical advances

Regulation of epigenetic modifications on chromatin. Chromatin can be classified according to the local structure of the basic repeating unit, the nucleosome, which is made of DNA and histones. Chroma....

2024-01-31

MedComm-Future Medicine | Cryoprotectants for red blood cells: Evaluate safety and effectiveness by in vitro measures

History of the development of small molecule- and macromolecule-based cryoprotectants for red blood cell cryopreservation. DMSO, dimethyl sulfoxide.The transfusion of red blood cells (RBCs) is crucial....

2023-12-31

MedComm-Biomaterials and Applications | Development of nanoparticle-based drug delivery system for inflammation treatment and diagnosis

Schematic diagram of nanoparticles, cells carrying nanoparticles, and nanoparticles encapsulated by cell membranes in the site of vascular inflammation. The lower part of the figure is classification ....

2023-12-31

MedComm-Oncology | Cancer stem cells: Signaling pathways and therapeutic targeting

This figure explains the origin of cancer stem cells (CSCs) and the cause of conventional antitumor therapy failure due to the survival capability of these CSCs under the extreme conditions created du....

2023-12-31