Direct cellular targets of oridonin and the functions of oridonin-binding proteins. For each protein and associated pathway, the extent of inhibition depends on the concentration of oridonin applied. ....
2023-04-30
Ocular neovascular diseases. (A) Normal eye structure. (B) Normal retinal structure of a representative area of a normal eye (the rectangular area in A). (C) In wet age-related macular degeneration (w....
2023-03-31
Dysregulation and mutation profile of RNA modification regulators in pan-cancer. (A) The relative expression level of RNA modification regulators across cancer types. (B) The mutation frequencies of R....
2023-02-28
Potential antivirals in VDDB. (A) Annotated entry for each vaccine. (B) Annotated entry for each antibody. (C) Annotated entry for each small molecule. (D) Classification of viruses.Virus infection is....
2023-01-31
DNA origami technology. (A) Schematic shows the fabrication process of classic DNA origami nanostructures. (B) Representative two-dimensional DNA origami shapes. (C) Representative three-dimensional m....
2023-07-31
The strategy and applications of copper metabolism-based cancer therapy.Copper (Cu) is an essential trace element in the human body that is involved in the formation of several natural enzymes, such a....
2023-06-30
(A) Orodispersible films (ODFs) embedded with poorly water-soluble active pharmaceutical ingredients (APIs) formulated by various formulation strategies (image reprinted with permission from Ref.Orodi....
2023-05-31
Mechanism of radiotherapy-induced abscopal effect combined with immunotherapy. CTLA-4, cytotoxic T-lymphocyte-associated antigen 4; PD-1, programmed death 1; PD-L1, programmed death-ligand 1; TNBC, tr....
2023-04-30
Two major barriers to topical ocular drug delivery. Reprinted with permission from Li et al.Due to high structural flexibility, multidrug carrying capability, and tunable size, dendrimers have been us....
2023-03-31