MedComm-Future Medicine | Awareness of high and pathological myopia among myopic patients in China: A cross-sectional multicenter survey

Flowchart depicting the screening process for the study participants.This study aimed to investigate the awareness of high and pathological myopia among patients with high myopia. A cross-sectional mu....

2023-11-30

MedComm-Biomaterials and Applications | Advances in organ-on-a-chip for the treatment of cardiovascular diseases

This figure compares OoC with 2D cell culture, organoids, and animal models and outlines the advantages and disadvantages. Figures were created with Photoshop CS6.Cardiovascular disease (CVD) is curre....

2023-11-30

MedComm-Oncology | COVID-19 and cancer: Dichotomy of the menacing dilemma

Characteristics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The diagram summarizes the taxonomy, symptoms, pathophysiology, and variants of the SARS-CoV-2 virus.The coronavirus di....

2023-11-30

MedComm-Future Medicine | Oncolytic viral therapy as promising immunotherapy against glioma

Antitumor effects of oncolytic virus (OVs) in brain tumor. (1) OVs can selectively infect tumor cells and induce tumor cells lysis including apoptosis, pyroptosis, and necroptosis. (2) Innate immune r....

2023-10-31

MedComm-Biomaterials and Applications | Exploring the potential of transethosomes in therapeutic delivery: A comprehensive review

Schematic illustration of various lipid-based nanocarriers with phospholipid, ethanol, and surfactant (liposome, transethosome, transferosome, and ethosome).The growing need for innovative drug delive....

2023-10-31

MedComm-Oncology | Development of covalent inhibitors: Principle, design, and application in cancer

Number of publications found in the SciFinder® search for covalent inhibitors closely related to targeting different amino acid residues.Covalent inhibitors have been a rapidly growing field in drug d....

2023-10-31

MedComm-Future Medicine | Metabolic insights into tumor pathogenesis: Unveiling pan-cancer metabolism and the potential of untargeted metabolomics

Metabolic profile of normal and tumor cells. Normal cells provide energy primarily through the tricarboxylic acid cycle, while tumor cells provide energy primarily through glycolysis even in the prese....

2023-09-30

MedComm-Biomaterials and Applications | Melatonin: Avenues in cancer therapy and its nanotechnological advancements

Prokaryotes to eukaryotes: MLT-preserved characteristics.Cancer is one of the most prevailing causes of mortality worldwide. Standard therapies for cancer patients include surgical intervention, chemo....

2023-09-30

MedComm-Oncology | Applications of macrocyclic molecules in cancer therapy: Target cancer development or overcome drug resistance

The structures of approved macrocyclic drugs and investigating macrocyclic compounds for cancer therapy.(A) Macrocyclic compounds to target cancer development. Compounds 1–2: macrocyclic peptide drugs....

2023-09-30