Schematic diagram of protein phosphorylation signaling pathway of protein kinase A, G, and C (AGC)-receptor guanylate cyclase (RGC) groupProtein phosphorylation is an important post-transcriptional mo....
2022-11-03
MedComm
The altered brain and platelet key proteins and their network linkage in AD patients.Platelets may serve as a perfect peripheral source for exploring diagnostic biomarkers for Alzheimer's disease (AD)....
2022-10-13
MedComm
Mechanisms of secondary resistance of small molecule inhibitors and countermeasuresCompared with traditional therapies, targeted therapy has merits in selectivity, efficacy, and tolerability. Small mo....
2022-10-13
MedComm
Crosstalk in the metabolism organs of cancer cachexia. Cancer cachexia is a complex systemic catabolism syndrome characterized by muscle wasting. It affects multiple distant organs and their crosstalk....
2022-09-10
MedComm
Intervention therapy of epigenetic regulators targeting inflammation-related diseasesEmerging evidence indicates that resolution of inflammation is a critical and dynamic endogenous process for host t....
2022-09-15
MedComm
The roles of process of neutrophil extracellular trap (NET) formation (NETosis) in multiple diseasesEvidence shows that neutrophils can protect the host against pathogens in multiple ways, including t....
2022-08-19
MedComm
Immunomodulatory actions of HSPs in autoimmune diseasesThe heat shock proteins (HSPs) are ubiquitous and conserved protein families in both prokaryotic and eukaryotic organisms, and they maintain cell....
2022-08-02
MedComm
Schematic of the PI3K/AKT/mTOR and Raf/MEK/ERK signaling pathways.The PI3K/AKT/mTOR and RAF/MEK/ERK pathways are commonly activated by mutations and chromosomal translocation in vital targets. The PI3....
2022-12-21
Mol Biomed
Primary indications for antibody therapeutics are approved across the globe and in late-stage clinical studies sponsored by commercial firmsSince the first monoclonal antibody drug, muromonab-CD3, was....
2022-11-22
Mol Biomed