
Expression of miR-379-5p is decreased in vitro/in vivo/in clinic.Lipotoxicity induced by the overload of lipid in the liver, especially excess free cholesterol (FC), has been recognized as one of driv....
2022-08-10

Mol Biomed

Classification of infective human viral diseases and their characteristic sub division and familyA virus enters a living organism and recruits host metabolism to reproduce its own genome and proteins.....
2022-07-15

Mol Biomed

Schematic diagram of obtain CDR3 of neutralizing antibodies against SARS-CoV-2Although the SARS-CoV-2 vaccine has been widely used worldwide, not all individuals can produce neutralization antibodies,....
2022-07-05

Mol Biomed

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) dysregulates antiviral signaling, immune response, and cell metabolism in human body. Viral genome and proteins hijack host metabolic netwo....
2022-08-09

Major depressive disorder (MDD) is a highly prevalent and disabling disorder. Despite the many hypotheses proposed to understand the molecular pathophysiology of depression, it is still unclear. Curre....
2022-07-21

MedComm

The main proteases (Mpro), also termed 3-chymotrypsin-like proteases (3CLpro), are a class of highly conserved cysteine hydrolases in β-coronaviruses. Increasing evidence has demonstrated that 3CLpros....
2022-07-14

MedComm

Opioid abuse and addiction have become a global pandemic, posing tremendous health and social burdens. The rewarding effects and the occurrence of withdrawal symptoms are the two mainstays of opioid a....
2022-06-22

MedComm

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the coronavirus disease 2019 (COVID-19) global pandemic. Omicron, a new variant of SARS-CoV-2, has the characteristics of strong....
2022-06-03

Mol Biomed

Rheumatoid arthritis (RA) is a chronic autoimmune disorder affecting joints with a hallmark of autoantibody production. Mannan-enhanced collagen type II (COL2) antibody induced arthritis (mCAIA) in ne....
2022-05-12

Mol Biomed