MedComm | Regulatory T cells: A potential weapon to combat COVID‐19?

Up to May 27th, there are at least 352 460 patients died from COVID-19, attributed to the widely spread novel coronavirus SARS‐CoV‐2. An effective treatment against COVID-19 is desiderated. Song Guo Z....



Breaking News! First Publication of Molecular Biomedicine——Structural characterization of the C-terminal domain of SARS-CoV-2 nucleocapsid protein

A new member of OA at Springer has recently published its first journal article. Molecular Biomedicine is a peer-reviewed, online open access, multidisciplinary journal that publishes the pioneer work....


Mol Biomed

MedComm | Pulmonary Staphylococcus aureus infection regulates breast cancer cell metastasis via neutrophil extracellular traps (NETs) formation

Neutrophil extracellular traps (NETs) has been demonstrated as of ultmost importance for host tissue homeostasis in bacteria infection. Since a large proportion of cancer patients receiving immunother....



MedComm | Mitochondria as a target in cancer treatment

Mitochondria are biosynthetic, bioenergetic, and signaling organelles existing in almost all eukaryotic cells, and their dysregulated function has been proved to be essential for tumorigenesis, tumor ....



MedComm | De novo lipogenesis is elicited dramatically in human hepatocellular carcinoma especially in hepatitis C virus‐induced hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths worldwide, which has drew much attention of researchers. Notably, it has been proved that, in the process of hepatocarcinogen....



MedComm | Neurologic manifestations of nonhospitalized patients with COVID‐19 in Wuhan, China

The coronavirus disease 2019 (COVID‐19) had spread to every continent, with more than 4 million confirmed cases all over the world by May 9, 2020. However, due to lack of awareness of the atypical neu....



MedComm | Enhancing anticancer activity of checkpoint immunotherapy by targeting RAS

Though checkpoint immunotherapy has seemed to achieve much success in clinic application these days, a huge proportion of patients with RAS-driven tumors are still suffering from resistance



MedComm | Vitamin intervention for cytokine storm in the patients with coronavirus disease 2019

Recently, Jian‐Sheng Kang reported a strategy for protecting patients with COVID-19, based on vitamin intervention for cytokine storm. As the global pandemic is still growing, if the vitamin intervent....



MedComm | A dual MET/AXL small‐molecule inhibitor exerts efficacy against gastric carcinoma through killing cancer cells as well as modulating tumor microenvironment

There are two kinds of receptor tyrosine kinases --MET and AXL --which are intimately bound up with tumorigenesis and aggressiveness of multiple malignancies. However, the molecular mechanism of MET a....